P2RX7 抗体 (Center)
(1 reference)-
- 抗原 See all P2RX7 抗体
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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抗原表位
- Center
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This P2RX7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠, 牛
- 交叉反应 （详细）
- Mouse (82 %), Bovine (86 %)
- 产品特性
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Rabbit Polyclonal antibody to P2X7 (purinergic receptor P2X, ligand-gated ion channel, 7)
P2X7 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human P2X7. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product P2RX7 Primary Antibody
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anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 226-452) antibody
P2RX7 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G1D6 unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibodyP2RX7 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular Loop) antibodyP2RX7 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular Loop) antibody (FITC)P2RX7 适用: 人, 小鼠, 大鼠 FACS, IF, ICC, LCI 宿主: 兔 Polyclonal FITC
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 576-595), (C-Term), (Intracellular) antibody (Atto 550)P2RX7 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal Atto 550
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 47-334) antibodyP2RX7 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (C-Term) antibodyP2RX7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibodyVerified P2RX7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 563-592) antibodyP2RX7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21714 unconjugated
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- 应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- 说明
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Positive Control: A431 , Rat brain
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Pannexin 3 activates P2X7 receptor to mediate inflammation and cartilage matrix degradation in temporomandibular joint osteoarthritis." in: Cell biology international, Vol. 47, Issue 7, pp. 1183-1197, (2023) (PubMed).
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: "Pannexin 3 activates P2X7 receptor to mediate inflammation and cartilage matrix degradation in temporomandibular joint osteoarthritis." in: Cell biology international, Vol. 47, Issue 7, pp. 1183-1197, (2023) (PubMed).
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- 抗原
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- 别名
- P2X7 (P2RX7 产品)
- 别名
- p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
- 背景
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The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria.
Cellular Localization: Membrane, Multi-pass membrane protein - 分子量
- 69 kDa
- 基因ID
- 5027
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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