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SYVN1 抗体 (N-Term)

Name: SYVN1 抗体 (N-Term)
SKU: ABIN650702
Availability: OutOfStock

SYVN1 适用: 人 WB 宿主: 兔 Polyclonal RB15288 unconjugated

Western blot analysis of HRD1 Antibody (N-term) (ABIN650702 and ABIN2839220) in SK-BR-3 cell line lysates (35 μg/lane). (SYVN1 抗体 (N-Term))

1 image

(4 references)

产品编号 ABIN650702

发货至: 中国

Datasheet as PDF

抗原 See all SYVN1 抗体

SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))
抗原表位
16

8

5

5

5

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 106-138, N-Term
适用
54

36

10

7

6

5

4

4

3

3

2

2

2

1

1

1
人
宿主
50

2

2
兔
Compatible Secondaries
克隆类型
52

2
多克隆
标记
30

4

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1
This SYVN1 antibody is un-conjugated
应用范围
45

22

15

13

13

13

7

5

4

3

1

1
Western Blotting (WB)

预测反应

M, X

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This HRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-138 amino acids from the N-terminal region of human HRD1.

克隆位点

RB15288

亚型

Ig Fraction

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anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 586-617) antibody
SYVN1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibody
Verified SYVN1 适用: 人, 大鼠 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated

anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 531-617) antibody
SYVN1 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibody
SYVN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 338-487) antibody
SYVN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (Internal Region) antibody
SYVN1 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, Bat, 猴, 斑马鱼, Hamster, 非洲爪蟾 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 1-617) antibody
SYVN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 238-318) antibody
SYVN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated

anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 501-550) antibody
SYVN1 适用: 人, 小鼠, 大鼠, 马, 豚鼠, Bat WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Di, Wang, Han, Fu, Duerfeldt, Blagg, Mu: "Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9526-39, (2016) (PubMed).

van den Boomen, Timms, Grice, Stagg, Skødt, Dougan, Nathan, Lehner: "TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 31, pp. 11425-30, (2014) (PubMed).

Wang, Yu, Guo, Zuo, Fisher, Subjeck, Wang: "Enhanced endoplasmic reticulum entry of tumor antigen is crucial for cross-presentation induced by dendritic cell-targeted vaccination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 12, pp. 6010-21, (2013) (PubMed).

Burr, van den Boomen, Bye, Antrobus, Wiertz, Lehner: "MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 35, pp. 14290-5, (2013) (PubMed).
抗原

SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))

别名

HRD1 (SYVN1 产品)

别名

DER3 antibody, HRD1 antibody, hrd1 antibody, 1200010C09Rik antibody, AW211966 antibody, C85322 antibody, D530017H19Rik antibody, Hrd1 antibody, RGD1310488 antibody, syvn1 antibody, syvn1-a antibody, syvn1-b antibody, wu:fk91f10 antibody, zgc:55735 antibody, zgc:77108 antibody, synoviolin 1 antibody, synovial apoptosis inhibitor 1, synoviolin antibody, synoviolin 1 S homeolog antibody, SYVN1 antibody, syvn1 antibody, Syvn1 antibody, syvn1.S antibody

背景

HRD1 encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence.

分子量

67685

NCBI登录号

NP_115807, NP_757385

UniProt

Q86TM6

途径

ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling