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MDM2 抗体

MDM2 适用: 人 IHC (p), IP, IHC (fro), IHC (rs) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN643838
发货至: 中国
  • 抗原 See all MDM2 抗体
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MDM2 antibody is un-conjugated
    应用范围
    • 123
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Resin Sections) (IHC (rs))
    原理
    Mouse Anti-Human MDM2
    特异性
    DS-MB-01877 recognizes the 90kD MDM2 protein, which forms a complex with p53 leading to p53 inhibition. DS-MB-01877 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. It is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer. reacts with: Mouse. Antibody reactivity and working conditions may vary between species.
    产品特性
    Transcription and its regulation
    纯化方法
    Purified
    免疫原
    Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2.
    亚型
    IgG1
    Top Product
    Discover our top product MDM2 Primary Antibody
  • 应用备注
    Immunohistology - Frozen, Immunoprecipitation, Immunohistology - Paraffin, Immunohistology - Resin
    限制
    仅限研究用
  • 浓度
    IgG concentration 1.0 mg/ml
    缓冲液
    Phosphate buffered saline pH7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
    别名
    MDM2 (MDM2 产品)
    别名
    ACTFS antibody, HDMX antibody, hdm2 antibody, zgc:109834 antibody, 1700007J15Rik antibody, AA415488 antibody, Mdm-2 antibody, MDM2 proto-oncogene antibody, MDM2 proto-oncogene S homeolog antibody, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antibody, MDM2 oncogene, E3 ubiquitin protein ligase antibody, transformed mouse 3T3 cell double minute 2 antibody, MDM2 antibody, mdm2.S antibody, Mdm2 antibody, mdm2 antibody
    途径
    p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway
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