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- 抗原 See all DKK1 抗体
- DKK1 (Dickkopf Homolog 1 (DKK1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DKK1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit Anti-Human DKK1
- 特异性
- DS-PB-00648 recognizes human Dickkopf (Xenopus laevis) homolog 1 (DKK1), a 35kDa to 50kDa member of the dickkopf family. It is expressed in the placenta, prostate and to a lesser extent, in the colon and spleen. DKK1 is secreted when expressed in 293T cells. DKK1 inhibits Wnt signalling in embryonic development, most likely acting upstream of frizzled. It is also thought to contribute to neoplastic processes, inhibit osteoblast differentiation and is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
- 纯化方法
- Purified
- 免疫原
- Synthetic human DKK1 - KLH conjugated.
- 亚型
- IgG
- Top Product
- Discover our top product DKK1 Primary Antibody
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- 应用备注
- Immunohistology - Paraffin
- 限制
- 仅限研究用
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- 浓度
- IgG concentration 1.0 mg/ml
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C
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Evaluation of circulating levels of inflammatory and bone formation markers in axial spondyloarthritis." in: International immunopharmacology, Vol. 21, Issue 2, pp. 481-6, (2014) (PubMed).
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Evaluation of circulating levels of inflammatory and bone formation markers in axial spondyloarthritis." in: International immunopharmacology, Vol. 21, Issue 2, pp. 481-6, (2014) (PubMed).
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- 抗原
- DKK1 (Dickkopf Homolog 1 (DKK1))
- 别名
- DKK1 (DKK1 产品)
- 别名
- DKK-1 antibody, SK antibody, AI414495 antibody, SGY antibody, SGY-1 antibody, SGY1 antibody, Soggy antibody, mSgy antibody, dkk1 antibody, dkk antibody, dkk-1 antibody, xdkk1 antibody, Xdkk-1 antibody, Dickkopf1 antibody, dickkopf-1 antibody, mdkk-1 antibody, dkk1-A antibody, dickkopf WNT signaling pathway inhibitor 1 antibody, dickkopf like acrosomal protein 1 antibody, dickkopf-related protein 1 antibody, dickkopf-like 1 antibody, dickkopf WNT signaling pathway inhibitor 1b antibody, dickkopf protein antibody, dickkopf WNT signaling pathway inhibitor 1 S homeolog antibody, DKK1 antibody, Dkk1 antibody, DKKL1 antibody, LOC100228789 antibody, Dkkl1 antibody, dkk1b antibody, dkk1 antibody, dickkopf antibody, dkk1.S antibody
- 途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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