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CLEC7A 抗体

CLEC7A 适用: 人 FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN641413
发货至: 中国
  • 抗原 See all CLEC7A 抗体
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    适用
    • 55
    • 36
    • 6
    • 1
    宿主
    • 40
    • 17
    • 16
    小鼠
    克隆类型
    • 41
    • 27
    单克隆
    标记
    • 24
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    This CLEC7A antibody is un-conjugated
    应用范围
    • 42
    • 37
    • 23
    • 22
    • 9
    • 8
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    • 1
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    Flow Cytometry (FACS)
    原理
    Mouse Anti-Human Dectin-1
    特异性
    129-10231 recognizes human Dectin-1, also known as beta-glucan receptor (betaGR), a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells. Human Dectin-1 has two major (betaGR-A and betaGR-B) and several minor isoforms. betaGR-A and betaGR-B differs by the presence and absence, respectively, of a stalk region. 129-10231 recognizes both of these isoforms. This antibody could be used to inhibit receptor function.
    纯化方法
    Purified
    免疫原
    NIH3T3 cells expressing full length Beta-glucan receptor.
    亚型
    IgG1
    Top Product
    Discover our top product CLEC7A Primary Antibody
  • 应用备注
    Flow Cytometry
    限制
    仅限研究用
  • 浓度
    IgG concentration 1.0 mg/ml
    缓冲液
    Phosphate buffered saline pH7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    别名
    Dectin-1 (CLEC7A 产品)
    别名
    CLEC7A antibody, BGR antibody, Clecsf12 antibody, beta-GR antibody, CANDF4 antibody, CLECSF12 antibody, DECTIN1 antibody, Clec7b antibody, RGD1565140 antibody, C-type lectin domain containing 7A antibody, C-type lectin domain family 7, member a antibody, CLEC7A antibody, Clec7a antibody
    途径
    Activation of Innate immune Response
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