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CLEC7A 抗体 (Middle Region)

This anti-CLEC7A antibody is a 兔 多克隆 antibody detecting CLEC7A in WB, IHC (p), IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1449932
发货至: 中国

Quick Overview for CLEC7A 抗体 (Middle Region) (ABIN1449932)

抗原

See all CLEC7A 抗体
CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

适用

  • 60
  • 46
  • 4
  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 19
  • 17

克隆类型

  • 48
  • 30
多克隆

标记

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  • 6
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CLEC7A antibody is un-conjugated

应用范围

  • 46
  • 38
  • 23
  • 22
  • 9
  • 8
  • 8
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 10
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    17 amino acid synthetic peptide near the center of Human CLEC7A

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

    别名

    CLEC7A / Dectin-1

    背景

    CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.Synonyms: BGR, Beta-glucan receptor, C-type lectin domain family 7 member A, C-type lectin superfamily member 12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, Dendritic cell-associated C-type lectin 1

    基因ID

    64581

    NCBI登录号

    NP_922938

    途径

    Activation of Innate immune Response
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