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CLEC7A 抗体 (Middle Region)

CLEC7A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449932
发货至: 中国
  • 抗原 See all CLEC7A 抗体
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    抗原表位
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    Middle Region
    适用
    • 56
    • 35
    • 5
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    人, 小鼠, 大鼠
    宿主
    • 40
    • 17
    • 17
    克隆类型
    • 41
    • 28
    多克隆
    标记
    • 24
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    • 4
    • 1
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    • 1
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    This CLEC7A antibody is un-conjugated
    应用范围
    • 43
    • 37
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    • 8
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    17 amino acid synthetic peptide near the center of Human CLEC7A
    亚型
    IgG
    Top Product
    Discover our top product CLEC7A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    别名
    CLEC7A / Dectin-1 (CLEC7A 产品)
    别名
    CLEC7A antibody, BGR antibody, Clecsf12 antibody, beta-GR antibody, CANDF4 antibody, CLECSF12 antibody, DECTIN1 antibody, Clec7b antibody, RGD1565140 antibody, C-type lectin domain containing 7A antibody, C-type lectin domain family 7, member a antibody, CLEC7A antibody, Clec7a antibody
    背景
    CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.Synonyms: BGR, Beta-glucan receptor, C-type lectin domain family 7 member A, C-type lectin superfamily member 12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, Dendritic cell-associated C-type lectin 1
    基因ID
    64581
    NCBI登录号
    NP_922938
    途径
    Activation of Innate immune Response
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