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Perforin 1 抗体

PRF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN634500
发货至: 中国
  • 抗原 See all Perforin 1 (PRF1) 抗体
    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
    适用
    • 80
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    • 1
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    宿主
    • 57
    • 41
    • 4
    克隆类型
    • 58
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    多克隆
    标记
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    This Perforin 1 antibody is un-conjugated
    应用范围
    • 50
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    Western Blotting (WB)
    纯化方法
    Affinity purified
    免疫原
    Perforin 1 antibody was raised using a synthetic peptide corresponding to a region with amino acids SVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPDFKR
    Top Product
    Discover our top product PRF1 Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    Perforin 1 Blocking Peptide, catalog no. 33R-8899, is also available for use as a blocking control in assays to test for specificity of this Perforin 1 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PRF1 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
    别名
    Perforin 1 (PRF1 产品)
    别名
    FLH2 antibody, HPLH2 antibody, P1 antibody, PFN1 antibody, PFP antibody, PRF1 antibody, Pfn antibody, Pfp antibody, Prf-1 antibody, Cyta antibody, RATCYTA antibody, LOC443187 antibody, perforin antibody, prf1 antibody, cytolysin antibody, perforin-1 antibody, perforin-1-like antibody, perforin 1 antibody, perforin 1 (pore forming protein) antibody, perforin antibody, perforin 1 L homeolog antibody, PRF1 antibody, Prf1 antibody, LOC443187 antibody, prf1 antibody, prf1.L antibody
    背景
    PRF1 has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in the gene encoding PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood.
    分子量
    59 kDa (MW of target protein)
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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