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MLH3 抗体

MLH3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN634149
发货至: 中国
  • 抗原 See all MLH3 抗体
    MLH3 (MutL Homolog 3 (MLH3))
    适用
    • 17
    • 1
    • 1
    • 1
    宿主
    • 16
    • 1
    克隆类型
    • 17
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MLH3 antibody is un-conjugated
    应用范围
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purified
    免疫原
    MLH3 antibody was raised using a synthetic peptide corresponding to a region with amino acids SMQVLQQVDNKFIACLMSTKTEENGEADSYEKQQAQGSGRKKLLSSTLIP
    Top Product
    Discover our top product MLH3 Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    MLH3 Blocking Peptide, catalog no. 33R-8644, is also available for use as a blocking control in assays to test for specificity of this MLH3 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MLH3 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    MLH3 (MutL Homolog 3 (MLH3))
    别名
    MLH3 (MLH3 产品)
    别名
    AV125803 antibody, BB126472 antibody, MGC80774 antibody, MLH3 antibody, HNPCC7 antibody, mutL homolog 3 antibody, mutL homolog 3 L homeolog antibody, Mlh3 antibody, mlh3.L antibody, MLH3 antibody, mlh3 antibody
    背景
    This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
    分子量
    161 kDa (MW of target protein)
    途径
    Chromatin Binding
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