MLH3 抗体
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- 抗原 See all MLH3 抗体
- MLH3 (MutL Homolog 3 (MLH3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MLH3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purified
- 免疫原
- MLH3 antibody was raised using a synthetic peptide corresponding to a region with amino acids SMQVLQQVDNKFIACLMSTKTEENGEADSYEKQQAQGSGRKKLLSSTLIP
- Top Product
- Discover our top product MLH3 Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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MLH3 Blocking Peptide, catalog no. 33R-8644, is also available for use as a blocking control in assays to test for specificity of this MLH3 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MLH3 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- MLH3 (MutL Homolog 3 (MLH3))
- 别名
- MLH3 (MLH3 产品)
- 别名
- AV125803 antibody, BB126472 antibody, MGC80774 antibody, MLH3 antibody, HNPCC7 antibody, mutL homolog 3 antibody, mutL homolog 3 L homeolog antibody, Mlh3 antibody, mlh3.L antibody, MLH3 antibody, mlh3 antibody
- 背景
- This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
- 分子量
- 161 kDa (MW of target protein)
- 途径
- Chromatin Binding
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