MLH3 抗体 (AA 521-570)
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北京 101111
Quick Overview for MLH3 抗体 (AA 521-570) (ABIN1534469)
抗原
See all MLH3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 521-570
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原理
- MLH3 Antibody
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特异性
- MLH3 Polyclonal Antibody detects endogenous levels of MLH3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MLH3. AA range:521-570
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MLH3 (MutL Homolog 3 (MLH3))
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别名
- MLH3
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背景
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Synonyms: MLH3, DNA mismatch repair protein Mlh3, MutL protein homolog 3
Background: This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination.The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],
Gene Name: MLH3
Protein Name: DNA mismatch repair protein Mlh3
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分子量
- 163 kDa
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基因ID
- 27030
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OMIM
- 114500
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UniProt
- Q9UHC1
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途径
- Chromatin Binding
抗原
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