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TRPM4 抗体 (N-Term)

TRPM4 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN633730
发货至: 中国
  • 抗原 See all TRPM4 抗体
    TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))
    抗原表位
    • 16
    • 15
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    • 1
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    • 1
    N-Term
    适用
    • 40
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    人, 大鼠, 小鼠
    宿主
    • 40
    • 3
    克隆类型
    • 40
    • 3
    多克隆
    标记
    • 18
    • 3
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    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    This TRPM4 antibody is un-conjugated
    应用范围
    • 41
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    Western Blotting (WB)
    特异性
    TRPM4 antibody was raised against the N terminal of TRPM4
    纯化方法
    Affinity purified
    免疫原
    TRPM4 antibody was raised using the N terminal of TRPM4 corresponding to a region with amino acids ELLTVYSSEDGSEEFETIVLKALVKACGSSEASAYLDELRLAVAWNRVDI
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    Discover our top product TRPM4 Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    TRPM4 Blocking Peptide, catalog no. 33R-2560, is also available for use as a blocking control in assays to test for specificity of this TRPM4 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TRPM4 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))
    别名
    TRPM4 (TRPM4 产品)
    别名
    PFHB1B antibody, TRPM4B antibody, LTrpC-4 antibody, Mls2s antibody, 1110030C19Rik antibody, AW047689 antibody, LTRPC4 antibody, TRPM4 antibody, transient receptor potential cation channel subfamily M member 4 antibody, transient receptor potential cation channel, subfamily M, member 4 antibody, TRPM4 antibody, Trpm4 antibody
    背景
    TRPM4 is a calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca2+, it is impermeable to it. TRPM4 mediates transport of monovalent cations (Na+ > K+ > Cs+ > Li+), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production.
    分子量
    134 kDa (MW of target protein)
    途径
    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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