TRPM4 抗体 (N-Term)
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- 抗原 See all TRPM4 抗体
- TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRPM4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- TRPM4 antibody was raised against the N terminal of TRPM4
- 纯化方法
- Affinity purified
- 免疫原
- TRPM4 antibody was raised using the N terminal of TRPM4 corresponding to a region with amino acids ELLTVYSSEDGSEEFETIVLKALVKACGSSEASAYLDELRLAVAWNRVDI
- Top Product
- Discover our top product TRPM4 Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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TRPM4 Blocking Peptide, catalog no. 33R-2560, is also available for use as a blocking control in assays to test for specificity of this TRPM4 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TRPM4 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))
- 别名
- TRPM4 (TRPM4 产品)
- 别名
- PFHB1B antibody, TRPM4B antibody, LTrpC-4 antibody, Mls2s antibody, 1110030C19Rik antibody, AW047689 antibody, LTRPC4 antibody, TRPM4 antibody, transient receptor potential cation channel subfamily M member 4 antibody, transient receptor potential cation channel, subfamily M, member 4 antibody, TRPM4 antibody, Trpm4 antibody
- 背景
- TRPM4 is a calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca2+, it is impermeable to it. TRPM4 mediates transport of monovalent cations (Na+ > K+ > Cs+ > Li+), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production.
- 分子量
- 134 kDa (MW of target protein)
- 途径
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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