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TRPM4 抗体 (N-Term)

Name: TRPM4 抗体 (N-Term)
SKU: ABIN2776221
Availability: OutOfStock

TRPM4 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-TRPM4 Antibody Titration: 0. (TRPM4 抗体 (N-Term))

Host: Rat Target Name: TRPM4 Sample Tissue: Rat Brain Antibody Dilution: 1ug/ml (TRPM4 抗体 (N-Term))

Host: Rabbit Target Name: TRPM4 Sample Type: Jurkat Antibody Dilution: 1. (TRPM4 抗体 (N-Term))

Host: Rabbit Target Name: TRPM4 Sample Type: MCF7 Antibody Dilution: 1. (TRPM4 抗体 (N-Term))

Host: Rabbit Target Name: TRPM4 Sample Type: 293T Antibody Dilution: 1. (TRPM4 抗体 (N-Term))

Host: Rabbit Target Name: TRPM4 Sample Type: 721_B Antibody Dilution: 1. (TRPM4 抗体 (N-Term))

Host: Rabbit Target Name: TRPM4 Sample Type: Hela Antibody Dilution: 1. (TRPM4 抗体 (N-Term))

Host: Rabbit Target Name: TRPM4 Sample Type: HepG2 Antibody Dilution: 1. (TRPM4 抗体 (N-Term))

8 images

(1 reference)

产品编号 ABIN2776221

发货至: 中国

Datasheet as PDF

抗原 See all TRPM4 抗体

TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))
抗原表位
16

15

10

2

2

2

1

1

1

1

1

1
N-Term
适用
41

22

21

2

2

2

1

1
人, 大鼠, 小鼠, Cow, 犬, 马, 豚鼠
宿主
41

3
兔
Compatible Secondaries
克隆类型
41

3
多克隆
标记
19

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1
This TRPM4 antibody is un-conjugated
应用范围
40

15

14

13

7

7

3

2

1

1

1
Western Blotting (WB)

序列

ELLTVYSSED GSEEFETIVL KALVKACGSS EASAYLDELR LAVAWNRVDI

预测反应

Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against TRPM4. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human TRPM4
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) antibody
TRPM4 适用: 人, 犬, 猴 WB, IHC 宿主: 小鼠 Monoclonal 10H5 unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) (AA 1-240) antibody
TRPM4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) (Internal Region) antibody
TRPM4 适用: 人, 大鼠, 小鼠, Cow IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) (N-Term) antibody
TRPM4 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) (AA 800-850) antibody
TRPM4 适用: 人, 大鼠, 小鼠 WB, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) (AA 1-400) antibody
TRPM4 适用: 大鼠 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) (AA 359-408) antibody
TRPM4 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) (C-Term) antibody
TRPM4 适用: 人, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) (AA 1-240) antibody
TRPM4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4) (AA 1079-1214) antibody
TRPM4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 1214 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Kuras, Yun, Chimote, Neumeier, Conforti: "KCa3.1 and TRPM7 channels at the uropod regulate migration of activated human T cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e43859, (2012) (PubMed).
抗原

TRPM4 (Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4))

别名

TRPM4 (TRPM4 产品)

别名

PFHB1B antibody, TRPM4B antibody, LTrpC-4 antibody, Mls2s antibody, 1110030C19Rik antibody, AW047689 antibody, LTRPC4 antibody, TRPM4 antibody, transient receptor potential cation channel subfamily M member 4 antibody, transient receptor potential cation channel, subfamily M, member 4 antibody, TRPM4 antibody, Trpm4 antibody

背景

TRPM4 is a calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca2+, it is impermeable to it. TRPM4 mediates transport of monovalent cations (Na+ > K+ > Cs+ > Li+), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. TRPM4 is involved in myogenic constriction of cerebral arteries. It controls insulin secretion in pancreatic beta-cells. TRPM4 may also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca2+ overload.
Alias Symbols: FLJ20041, TRPM4B, PFHB1B
Protein Interaction Partner: FUS, UBC, TRPM4,
Protein Size: 1214

分子量

134 kDa

基因ID

54795

NCBI登录号

NM_017636, NP_060106

UniProt

Q8TD43

途径

Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response