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- 抗原 See all AGAP2 抗体
- AGAP2 (ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AGAP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- CENTG1 antibody was raised against the middle region of CENTG1
- 纯化方法
- Affinity purified
- 免疫原
- CENTG1 antibody was raised using the middle region of CENTG1 corresponding to a region with amino acids AHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYGADVAARDAQG
- Top Product
- Discover our top product AGAP2 Primary Antibody
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anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (Internal Region) antibody
Verified AGAP2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (C-Term) antibodyAGAP2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (AA 20-60) antibodyAGAP2 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (AA 450-500) antibodyAGAP2 适用: 人, 小鼠, 大鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) antibodyAGAP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (AA 719-768) antibodyAGAP2 适用: 人, 小鼠, 大鼠, Cow, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (AA 1-836) antibodyAGAP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (AA 850-877), (C-Term) antibodyAGAP2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB19565 unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (C-Term) antibodyAGAP2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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CENTG1 Blocking Peptide, catalog no. 33R-1240, is also available for use as a blocking control in assays to test for specificity of this CENTG1 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CENTG1 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- AGAP2 (ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2))
- 别名
- CENTG1 (AGAP2 产品)
- 别名
- zgc:153779 antibody, CENTG1 antibody, GGAP2 antibody, PIKE antibody, Centg1 antibody, mKIAA0167 antibody, Pike antibody, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 antibody, AGAP2 antibody, agap2 antibody, Agap2 antibody
- 背景
- CENTG1 is a GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
- 分子量
- 90 kDa (MW of target protein)
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