AGAP2 抗体 (AA 981-1080)
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北京 101111
Quick Overview for AGAP2 抗体 (AA 981-1080) (ABIN759971)
抗原
See all AGAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 981-1080
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Centaurin gamma 1
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亚型
- IgG
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anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (Internal Region) antibody
Verified AGAP2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (AA 20-60) antibodyAGAP2 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (AA 450-500) antibodyAGAP2 适用: 人, 小鼠, 大鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (AA 719-768) antibodyAGAP2 适用: 人, 小鼠, 大鼠, Cow, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (AA 850-877), (C-Term) antibodyAGAP2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB19565 unconjugated
anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) (C-Term) antibodyAGAP2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- AGAP2 (ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2))
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别名
- Centaurin gamma 1
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背景
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Synonyms: Centaurin gamma 1, ANK repeat and PH domain-containing protein 2, AGAP-2, Agap2, Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2, AGAP2_HUMAN, ANK repeat and PH domains 2, Arf GAP with GTP binding protein like, Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2, Arf GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2, Arf-GAP with GTPase, Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2, centaurin gamma1, Centaurin-gamma-1, Centg1, cnt g1, Cnt-g1, Cnt2, GGAP2, GTP binding and GTPase activating protein 2, GTP-binding and GTPase activating protein 2, GTP-binding and GTPase-activating protein 2, Nuclear GTPase PIKE, Phosphatidylinositol-3-kinase enhancer, Phosphoinositide 3 kinase enhancer, PI3K ENHANCER, PIKE.
Background: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
抗原
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