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NSMCE2 抗体

NSMCE2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN631769
发货至: 中国
  • 抗原 See all NSMCE2 抗体
    NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
    适用
    • 24
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 22
    • 2
    克隆类型
    • 24
    多克隆
    标记
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NSMCE2 antibody is un-conjugated
    应用范围
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purified
    免疫原
    NSMCE2 antibody was raised using a synthetic peptide corresponding to a region with amino acids KFLALQSKNSDADFQNNEKFVQFKQQLKELKKQCGLQADREADGTEGVDE
    Top Product
    Discover our top product NSMCE2 Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    NSMCE2 Blocking Peptide, catalog no. 33R-4372, is also available for use as a blocking control in assays to test for specificity of this NSMCE2 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NSMCE2 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
    别名
    NSMCE2 (NSMCE2 产品)
    别名
    1110014D18Rik antibody, AI661537 antibody, RGD1305156 antibody, C8orf36 antibody, MMS21 antibody, NSE2 antibody, ZMIZ7 antibody, Non-SMC element 2 antibody, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase antibody, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog antibody, Smc5-6 complex non-SMC subunit 2 antibody, Nsmce2 antibody, NSMCE2 antibody, nsmce2.L antibody, nse2 antibody
    背景
    NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.
    分子量
    28 kDa (MW of target protein)
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