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NSMCE2 抗体

(E3 SUMO-Protein Ligase NSE2 (NSMCE2))
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).
NSMCE2 抗体  (AA 1-247) NSMCE2 抗体  (AA 1-247) NSMCE2 抗体 (AA 1-247) (ABIN531598)

NSMCE2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

NSMCE2 抗体  (AA 1-247) NSMCE2 抗体  (AA 1-247) NSMCE2 抗体 (AA 1-247) (ABIN7150959)

NSMCE2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

NSMCE2 抗体  (N-Term) NSMCE2 抗体  (N-Term) NSMCE2 抗体 (N-Term) (ABIN3185961)

NSMCE2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

NSMCE2 抗体 by 适用

Find NSMCE2 抗体 for a variety of species such as anti-Human NSMCE2, anti-Mouse NSMCE2, anti-Rabbit NSMCE2. The species listed below are among those available. Click on a link to go to the corresponding products.

NSMCE2 抗体 by 应用范围

Find NSMCE2 抗体 validated for a specific application such as WB, ELISA, IP, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

NSMCE2 抗体 by 抗体来源

Find NSMCE2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

NSMCE2 抗体 by 抗原表位

Find NSMCE2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

NSMCE2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal NSMCE2 抗体. Click on a link to go to the corresponding products.

NSMCE2 抗体 by 标记

Find NSMCE2 抗体 with a specific conjugate such as FITC, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular NSMCE2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
  • (2)
Cat. No. ABIN531598
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7150959
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN3185961
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Horse, Human, Pig, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN6755380
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IF (p)
Validations
Cat. No. ABIN1385784
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7150961
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7150962
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7150960
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
Cat. No. ABIN6991340
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
Cat. No. ABIN7450453
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IP
Validations
Cat. No. ABIN7451059
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IP
Validations
Cat. No. ABIN7451060
Quantity 100 μg
Datasheet Datasheet
Reactivity Horse, Human, Rabbit
Application IP
Validations
Cat. No. ABIN1914225
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Guinea Pig, Human, Rabbit
Application IP
Validations
Cat. No. ABIN1914224
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
Cat. No. ABIN2588457
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our NSMCE2 抗体

Verver, Zheng, Speijer, Hoebe, Dekker, Repping, Stap, Hamer: "Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress." in: International journal of molecular sciences, Vol. 17, Issue 11, (2016) (PubMed).

Ji, Bian, Yu, Yuan, Liu, Yu, Li, Zhu, Jia, Guan, Zhang, Meng, Jin, Bai, Yu, Lee, Sun, Fu: "Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 134, Issue 6, pp. 1279-88, (2014) (PubMed).

Chung, Leonhardt, Rippe: "De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation." in: Journal of cell science, Vol. 124, Issue Pt 21, pp. 3603-18, (2011) (PubMed).

Aliases for NSMCE2 抗体

NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2) 抗体
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2) 抗体
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L) 抗体
Smc5-6 complex non-SMC subunit 2 (nse2) 抗体
1110014D18Rik 抗体
AI661537 抗体
C8orf36 抗体
MMS21 抗体
Non-SMC element 2 抗体
NSE2 抗体
RGD1305156 抗体
ZMIZ7 抗体
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