NSMCE1 抗体
(Non-SMC Element 1 Homolog (NSMCE1))
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus.
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22 results
NSMCE1
适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 山羊, 猴
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Aliases for NSMCE1 抗体
NSE1 homolog, SMC5-SMC6 complex component (nsmce1) 抗体NSE1 homolog, SMC5-SMC6 complex component (NSMCE1) 抗体
NSE1 homolog, SMC5-SMC6 complex component L homeolog (nsmce1.L) 抗体
NSE1 homolog, SMC5-SMC6 complex component (Nsmce1) 抗体
2510027N19Rik 抗体
NSE1 抗体
NSMCE1 抗体
RGD1307760 抗体
zgc:92777 抗体
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