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CD36 抗体

CD36 适用: 人 FACS, IF, Func 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297679
发货至: 中国
  • 抗原 See all CD36 抗体
    CD36
    适用
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    宿主
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    • 69
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    小鼠
    克隆类型
    • 91
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    单克隆
    标记
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    This CD36 antibody is un-conjugated
    应用范围
    • 96
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    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    原理
    Mouse anti-Human CD36 Antibody [Sodium Azide Free]
    特异性
    Cell surface
    纯化方法
    Stimulated human leukocytes were used as the immunogen for the CD36 antibody.
    免疫原
    Stimulated human leukocytes were used as the immunogen for the CD36 antibody.
    Top Product
    Discover our top product CD36 Primary Antibody
  • 应用备注
    Functional Activity (Order SAF formulation) (1)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    CD36
    别名
    Platelet glycoprotein 4 (CD36 产品)
    别名
    BDPLT10 antibody, CHDS7 antibody, FAT antibody, GP3B antibody, GP4 antibody, GPIV antibody, PASIV antibody, SCARB3 antibody, Fat antibody, Scarb3 antibody, GPIIIB antibody, PAS-4 antibody, zgc:92513 antibody, CD36 molecule antibody, CD36 molecule (thrombospondin receptor) antibody, CD36 antibody, Cd36 antibody, cd36 antibody
    背景

    Target Description: CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. As a coreceptor for TLR4-TLR6 heterodimer, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion. [UniProt]

    Gene Symbol: CD36///GP3B///GP4

    基因ID
    948
    UniProt
    P16671
    途径
    TLR signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins
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