Insulin 抗体
Quick Overview for Insulin 抗体 (ABIN6297596)
抗原
See all Insulin (INS) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse/Rat Insulin Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- Recombinant INS protein was used as the immunogen for the Insulin antibody.
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免疫原
- Recombinant INS protein was used as the immunogen for the Insulin antibody.
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应用备注
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Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Insulin (INS)
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别名
- Insulin
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背景
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Target Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. [RefSeq]
Gene Symbol: INS
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基因ID
- 3630
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UniProt
- P01308
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途径
- NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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