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BAX 抗体

This 小鼠 单克隆 antibody specifically detects BAX in WB, IHC, ELISA, IF, FACS 和 Coat. It exhibits reactivity toward 人 和 猴.
产品编号 ABIN6296161
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BAX 抗体 (ABIN6296161)

抗原

See all BAX 抗体
BAX (BCL2-Associated X Protein (BAX))

适用

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人, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This BAX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
  • 原理

    Mouse anti-human/monkey Bax Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    Amino acids GSGEQPRGGGPTSS (3-16) were used as the immunogen for this anti-human Bax antibody.

    免疫原

    Amino acids GSGEQPRGGGPTSS (3-16) were used as the immunogen for this anti-human Bax antibody.
  • 应用备注

    ELISA: order BSA-free format for coating
    FACS: 0.5-1 μg/million cells
    IF: 1-2 μg/mL
    WB: 0.5-1 μg/mL
    IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS ( pH 7.4), BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    BAX (BCL2-Associated X Protein (BAX))

    别名

    Apoptosis regulator BAX

    背景

    Target Description: This antibody recognizes a protein of 21 kDa, identified as the Bax protein. The Bax antibody is highly specific and shows no cross-reaction with Bcl-2 alpha or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and the protein also counters the death repressor activity of Bcl-2.

    Gene Symbol: BAX///BCL2L4

    基因ID

    581

    UniProt

    Q07812

    途径

    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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