TRIM29 抗体 (AA 1-200)
Quick Overview for TRIM29 抗体 (AA 1-200) (ABIN6294234)
抗原
See all TRIM29 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-200
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原理
- Mouse anti-Human TRIM29 Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic & cell surface
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纯化方法
- A recombinant fragment (126 amino acid residues between aa 1-200) from the human protein was used as the immunogen for the TRIM29 antibody.
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免疫原
- A recombinant fragment (126 amino acid residues between aa 1-200) from the human protein was used as the immunogen for the TRIM29 antibody.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 0.5-1 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
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别名
- Tripartite motif-containing protein 29
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背景
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Target Description: It recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
Gene Symbol: TRIM29///ATDC
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基因ID
- 23650
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UniProt
- Q14134
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途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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