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TRIM29 抗体 (AA 1-200)

This anti-TRIM29 antibody is a 小鼠 单克隆 antibody detecting TRIM29 in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN6294234
发货至: 中国

Quick Overview for TRIM29 抗体 (AA 1-200) (ABIN6294234)

抗原

See all TRIM29 抗体
TRIM29 (Tripartite Motif Containing 29 (TRIM29))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TRIM29 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-200

    原理

    Mouse anti-Human TRIM29 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic & cell surface

    纯化方法

    A recombinant fragment (126 amino acid residues between aa 1-200) from the human protein was used as the immunogen for the TRIM29 antibody.

    免疫原

    A recombinant fragment (126 amino acid residues between aa 1-200) from the human protein was used as the immunogen for the TRIM29 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    TRIM29 (Tripartite Motif Containing 29 (TRIM29))

    别名

    Tripartite motif-containing protein 29

    背景

    Target Description: It recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

    Gene Symbol: TRIM29///ATDC

    基因ID

    23650

    UniProt

    Q14134

    途径

    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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