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- 抗原 See all Deoxyuridine Triphosphatase (DUT) 抗体
- Deoxyuridine Triphosphatase (DUT)
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human DUT
- 亚型
- IgG
- Top Product
- Discover our top product DUT Primary Antibody
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anti-Deoxyuridine Triphosphatase (DUT) (AA 68-164) antibody
DUT 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-Deoxyuridine Triphosphatase (DUT) antibodyDUT 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 89-252) antibodyDUT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (Internal Region) antibodyVerified DUT 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 151-252) antibodyDUT 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) antibodyDUT 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 1-252) antibodyDUT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibodyDUT 适用: 人, 大鼠, 小鼠, 犬, Bat, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (N-Term) antibodyDUT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 170-198), (C-Term) antibodyDUT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500 - 1:1000
- 说明
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Found in a variety of tissues, Isoform 3 expression is constitutive, while isoform 2 expression correlates with the onset of DNA replication (at protein level), Isoform 2 degradation coincides with the cessation of nuclear DNA replication (at protein level)
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- Deoxyuridine Triphosphatase (DUT)
- 别名
- DUT (DUT 产品)
- 别名
- BcDNA:LD08534 antibody, CG4584 antibody, Dmel\\CG4584 antibody, LD08534 antibody, UTPase antibody, anon-SAGE:Wang-077 antibody, dUTPase antibody, Tb07.27E10.390 antibody, dutpase antibody, 5031412I06Rik antibody, 5133400F09Rik antibody, D2Bwg0749e antibody, Dutp antibody, PIP4 antibody, deoxyuridine triphosphatase antibody, Deoxyuridine triphosphatase antibody, dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50 antibody, involved in nucleotide metabolism antibody, tegument protein antibody, dUTPase antibody, deoxyuridine triphosphatase L homeolog antibody, DUT antibody, dUTPase antibody, P18 antibody, AlHV1gp51 antibody, UL50 antibody, HVT058 antibody, ORF9 antibody, ORF8 antibody, U45 antibody, GAMMAHV.ORF54 antibody, Tc00.1047053509151.130 antibody, Tc00.1047053508175.160 antibody, Tb927.7.5160 antibody, dut.L antibody, Dut antibody
- 物质类
- Viral Protein
- 背景
- This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.
- 分子量
- 26.563 kDa
- 基因ID
- 1854
- UniProt
- P33316
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