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- 抗原 See all SIRT2 抗体
- SIRT2 (Sirtuin 2 (SIRT2))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIRT2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human SIRT2
- 亚型
- IgG
- Top Product
- Discover our top product SIRT2 Primary Antibody
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anti-Sirtuin 2 (SIRT2) (AA 288-389) antibody
SIRT2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 128-227) antibodySIRT2 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-Sirtuin 2 (SIRT2) (AA 165-187), (Middle Region) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 28-303) antibodySIRT2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 65-340) antibodySIRT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 65-340) antibodySIRT2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 1D4-H11-H11 unconjugated
anti-Sirtuin 2 (SIRT2) (C-Term) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 275-389) antibodySIRT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5H11H9 unconjugated
anti-Sirtuin 2 (SIRT2) (C-Term) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 - 说明
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Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex, Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver, Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues, Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level), Widely expressed, Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung, Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- SIRT2 (Sirtuin 2 (SIRT2))
- 别名
- SIRT2 (SIRT2 产品)
- 别名
- CG5085 antibody, D.mel2 antibody, Dmel\\CG5085 antibody, SIRT2 antibody, dSIRT2 antibody, sir2 antibody, Sirt2 antibody, BmSirt2 antibody, AtSRT2 antibody, SIRTUIN 2 antibody, T2K12.8 antibody, sirtuin 2 antibody, SIR2 antibody, SIR2L antibody, SIR2L2 antibody, 5730427M03Rik antibody, Sir2l antibody, wu:fb57d05 antibody, zgc:55966 antibody, zgc:77003 antibody, Sirtuin 2 antibody, sirtuin 2 antibody, sirtuin 2 S homeolog antibody, NAD-dependent deacetylase sirtuin 2 homolog antibody, sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) antibody, Sirt2 antibody, SIRT2 antibody, sirt2.S antibody, SRT2 antibody, sirt2 antibody
- 背景
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
- 分子量
- 43.182 kDa
- 基因ID
- 22933
- UniProt
- Q8IXJ6
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