WISP3 抗体
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- 抗原 See all WISP3 抗体
- WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WISP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human WISP3
- 亚型
- IgG
- Top Product
- Discover our top product WISP3 Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000
- 说明
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Predominant expression in adult kidney and testis and fetal kidney, Weaker expression found in placenta, ovary, prostate and small intestine, Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
- 别名
- WISP3 (WISP3 产品)
- 别名
- CCN6 antibody, LIBC antibody, PPAC antibody, PPD antibody, ENSMUSG00000062074 antibody, Gm735 antibody, WISP-3 antibody, RGD1564120 antibody, WISP3 antibody, si:dkey-119m7.6 antibody, WNT1 inducible signaling pathway protein 3 antibody, WISP3 antibody, Wisp3 antibody, wisp3 antibody
- 背景
- This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 39.293 kDa
- 基因ID
- 8838
- UniProt
- O95389
- 途径
- WNT signaling, Growth Factor Binding
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