SMARCA4 抗体
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- 抗原 See all SMARCA4 抗体
- SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMARCA4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human SMARCA4
- 亚型
- IgG
- Top Product
- Discover our top product SMARCA4 Primary Antibody
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- 应用备注
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WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:20 - 1:50 - 说明
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Colocalizes with ZEB1 in E-cadherin-negative cells from established lines, and stroma of normal colon as well as in de-differentiated epithelial cells at the invasion front of colorectal carcinomas (at protein level)
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
- 别名
- SMARCA4 (SMARCA4 产品)
- 别名
- SMARCA4 antibody, BAF190 antibody, BAF190A antibody, BRG1 antibody, MRD16 antibody, RTPS2 antibody, SNF2 antibody, SNF2L4 antibody, SNF2LB antibody, SWI2 antibody, hSNF2b antibody, brg-1 antibody, Brg1 antibody, HP1-BP72 antibody, SNF2beta antibody, SW1/SNF antibody, b2b692Clo antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 antibody, SMARCA4 antibody, Smarca4 antibody
- 背景
- The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 184.646 kDa
- 基因ID
- 6597
- UniProt
- P51532
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance
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