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KIF7 抗体

KIF7 适用: 人, 大鼠, 小鼠 IF 宿主: 小鼠 Monoclonal 3F8 unconjugated
产品编号 ABIN6288850
发货至: 中国
  • 抗原 See all KIF7 抗体
    KIF7 (Kinesin Family Member 7 (KIF7))
    适用
    • 24
    • 15
    • 15
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 20
    • 4
    小鼠
    克隆类型
    • 20
    • 4
    单克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIF7 antibody is un-conjugated
    应用范围
    • 12
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (IF)
    原理
    Kif 7 is a protein encoded by the KIF7 gene which is approximately 150,5 kDa. Kif 7 is localised to the cilium tip. It is involved in signalling by hedgehog and GPCR. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of a ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Kif 7 is expressed in embryonic stem cells and Jurkat T-cells. Mutations in the KIF7 gene may result in Bardet-Biedl syndrome. STJ96965 was developed from clone 3F8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous Kif 7 proteins.
    特异性
    The antibody detects endogenous Kif 7 proteins.
    产品特性
    Mouse monoclonal to Kif 7.
    纯化方法
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    免疫原
    Synthetic Peptide
    克隆位点
    3F8
    亚型
    IgG1
    Top Product
    Discover our top product KIF7 Primary Antibody
  • 应用备注
    IHC 1:200
    说明

    Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    KIF7 (Kinesin Family Member 7 (KIF7))
    别名
    Kif 7 (KIF7 产品)
    别名
    KIF7 antibody, DDBDRAFT_0204609 antibody, DDBDRAFT_0206583 antibody, DDB_0204609 antibody, DDB_0206583 antibody, ACLS antibody, HLS2 antibody, JBTS12 antibody, UNQ340 antibody, cos2 antibody, costal2 antibody, kinesin family member 7 antibody, KIF7 antibody, kif7 antibody, Kif7 antibody
    基因ID
    374654
    UniProt
    Q2M1P5
    途径
    Hedgehog Signaling
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