KIF7 抗体
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- 抗原 See all KIF7 抗体
- KIF7 (Kinesin Family Member 7 (KIF7))
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适用
- 人, 大鼠, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KIF7 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 原理
- Kif 7 is a protein encoded by the KIF7 gene which is approximately 150,5 kDa. Kif 7 is localised to the cilium tip. It is involved in signalling by hedgehog and GPCR. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of a ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Kif 7 is expressed in embryonic stem cells and Jurkat T-cells. Mutations in the KIF7 gene may result in Bardet-Biedl syndrome. STJ96965 was developed from clone 3F8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous Kif 7 proteins.
- 特异性
- The antibody detects endogenous Kif 7 proteins.
- 产品特性
- Mouse monoclonal to Kif 7.
- 纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- 免疫原
- Synthetic Peptide
- 克隆位点
- 3F8
- 亚型
- IgG1
- Top Product
- Discover our top product KIF7 Primary Antibody
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- 应用备注
- IHC 1:200
- 说明
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Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- KIF7 (Kinesin Family Member 7 (KIF7))
- 别名
- Kif 7 (KIF7 产品)
- 别名
- KIF7 antibody, DDBDRAFT_0204609 antibody, DDBDRAFT_0206583 antibody, DDB_0204609 antibody, DDB_0206583 antibody, ACLS antibody, HLS2 antibody, JBTS12 antibody, UNQ340 antibody, cos2 antibody, costal2 antibody, kinesin family member 7 antibody, KIF7 antibody, kif7 antibody, Kif7 antibody
- 基因ID
- 374654
- UniProt
- Q2M1P5
- 途径
- Hedgehog Signaling
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