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MME 抗体

MME 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 小鼠 Monoclonal 5B8 unconjugated
产品编号 ABIN6288762
发货至: 中国
  • 抗原 See all MME 抗体
    MME (Membrane Metallo-Endopeptidase (MME))
    适用
    • 182
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    人, 小鼠, 大鼠
    宿主
    • 97
    • 90
    • 2
    小鼠
    克隆类型
    • 102
    • 86
    • 2
    单克隆
    标记
    • 104
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    This MME antibody is un-conjugated
    应用范围
    • 112
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    CD10 is a protein encoded by the MME gene which is approximately 85,5 kDa. CD10 is localised to the cell membrane. It is involved in the innate immune system, respiratory electron transport, peptide hormone metabolism and hematopoietic cell lineage. It is a common acute lymphocytic leukaemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukaemia. It acts as a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon and enkephalins. CD10 is expressed in the kidney, the cells of the nervous system, liver, blood and bone marrow. Mutations in the MME gene may result in Charcot-Marie-Tooth disease. STJ96974 was developed from clone 5B8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous CD10 proteins.
    特异性
    The antibody detects endogenous CD10 proteins.
    产品特性
    Mouse monoclonal to CD10.
    纯化方法
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    免疫原
    Synthetic Peptide
    克隆位点
    5B8
    亚型
    IgG1
    Top Product
    Discover our top product MME Primary Antibody
  • 应用备注
    IHC 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    MME (Membrane Metallo-Endopeptidase (MME))
    别名
    CD10 (MME 产品)
    别名
    CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody
    物质类
    Chemical
    基因ID
    4311
    UniProt
    P08473
    途径
    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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