MICU1 抗体
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- 抗原 See all MICU1 抗体
- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MICU1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- MICU1 is a protein encoded by the MICU1 gene which is approximately 54,3 kDa. MICU1 is localised to the mitochondrion inner membrane and mitochondrion intermembrane space. It is involved in Ca, cAMP and lipid signalling and is an essential regulator of mitochondrial Ca2+ uptake under basal conditions. It interacts with a mitochondrial inner membrane Ca2+ channel and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. MICU1 is expressed in the nervous system, kidney, muscle, skin and thyroid. Mutations in the MICU1 gene may result in dermatitis. STJ97447 was developed from clone Mix and was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. The antibody detects endogenous MICU1 protein.
- 特异性
- The antibody detects endogenous MICU1 protein.
- 产品特性
- Mouse monoclonal to MICU1.
- 纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Recombinant Protein
- 克隆位点
- Mix
- 亚型
- IgG1
- Top Product
- Discover our top product MICU1 Primary Antibody
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- 应用备注
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WB 1:1000-2000
IHC 1:100-200 - 说明
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Expressed in epithelial cell lines. Strongly expressed in epidermal keratinocytes and dermal endothelial cells.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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