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PFKM 抗体 (Internal Region)

PFKM 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6287047
发货至: 中国
  • 抗原 See all PFKM 抗体
    PFKM (phosphofructokinase, Muscle (PFKM))
    抗原表位
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 69
    • 28
    • 23
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 61
    • 9
    • 8
    • 7
    克隆类型
    • 68
    • 17
    多克隆
    标记
    • 49
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PFKM antibody is un-conjugated
    应用范围
    • 66
    • 37
    • 29
    • 14
    • 12
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    PFKM is a protein encoded by the PKFM gene which is approximately 85,2 kDa. PFKM is localised to the cytoplasm. It is involved in glucose metabolism, carbon metabolism and AMP-activated protein kinase signalling. It exists as three isozymes which function as subunits of the mammalian tetramer phosphofructokinase. It catalyses the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. PFKM is expressed in the nervous system, muscle, heart, lung and kidney. Mutations in the PFKM gene may result in glycogen storage disease, mcardle disease and phosphoglycerate kinase deficiency. STJ95045 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PFKM protein.
    特异性
    PFKM Polyclonal Antibody detects endogenous levels of PFKM protein.
    产品特性
    Rabbit polyclonal to PFKM.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human PFKM.
    亚型
    IgG
    Top Product
    Discover our top product PFKM Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    PFKM (phosphofructokinase, Muscle (PFKM))
    别名
    PFKM (PFKM 产品)
    别名
    GSD7 antibody, PFK-1 antibody, PFK1 antibody, PFKA antibody, PFKX antibody, AI131669 antibody, PFK-A antibody, PFK-M antibody, Pfk-4 antibody, Pfk4 antibody, Pfka antibody, Pfkx antibody, Pfk-M antibody, M-PFK antibody, PFKM antibody, pfkm antibody, zgc:92344 antibody, pfk antibody, im:7137110 antibody, wu:fc58g11 antibody, phosphofructokinase, muscle antibody, phosphofructokinase, platelet antibody, phosphofructokinase, muscle a antibody, phosphofructokinase, muscle S homeolog antibody, phosphofructokinase, muscle b antibody, PFKM antibody, Pfkm antibody, PFKP antibody, pfkma antibody, pfkm.S antibody, pfkmb antibody
    分子量
    85 kDa
    基因ID
    5213
    UniProt
    P08237
    途径
    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
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