COL4a3 抗体 (Internal Region)
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- 抗原 See all COL4a3 (COL4A3) 抗体
- COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
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抗原表位
- AA 770-850, Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COL4a3 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit polyclonal to COL4A3.
- 特异性
- COL4A3 Polyclonal Antibody detects endogenous levels of COL4A3 protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human COL4A3
- 亚型
- IgG
- Top Product
- Discover our top product COL4A3 Primary Antibody
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- 应用备注
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IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000 - 说明
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Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. According to PubMed:8083201, alpha 3 type IV collagen is not detected in heart, brain, placenta, liver, pancreas, extrasynaptic muscle fibers, endoneurial and perineurial nerves, fetal brain, fetal heart and fetal liver. According to PubMed:7523402, alpha 3 type IV collagen is strongly expressed in pancreas, neuroretina and calvaria and not expressed in adrenal, ileum and skin. Isoform 1 and isoform 3 are strongly expressed in kidney, lung, suprarenal capsule, muscle and spleen, in each of these tissues isoform 1 is more abundant than isoform 3. Isoform 1 and isoform 3 are expressed at low levels in artery, fat, pericardium and peripherical nerve, but not in placenta, mesangium, skin, pleura and cultured umbilical endothelial cells.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
- 别名
- COL4A3 (COL4A3 产品)
- 别名
- zTumstatin antibody, [a]3(IV) antibody, alpha3(IV) antibody, collagen type IV alpha 3 chain antibody, collagen, type IV, alpha 3 antibody, COL4A3 antibody, col4a3 antibody, Col4a3 antibody
- 分子量
- 140 kDa
- 基因ID
- 1285
- UniProt
- Q01955
- 途径
- Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity
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