COL4a3 抗体 (AA 1571-1670)
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北京 101111
Quick Overview for COL4a3 抗体 (AA 1571-1670) (ABIN678128)
抗原
See all COL4a3 (COL4A3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1571-1670
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Tumstatin
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "The impairment of intramural periarterial drainage in brain after subarachnoid hemorrhage." in: Acta neuropathologica communications, Vol. 10, Issue 1, pp. 187, (2022) (PubMed).
: "T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 11, pp. 1135-1144, (2017) (PubMed).
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: "The impairment of intramural periarterial drainage in brain after subarachnoid hemorrhage." in: Acta neuropathologica communications, Vol. 10, Issue 1, pp. 187, (2022) (PubMed).
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- COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
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别名
- Tumstatin
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背景
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Synonyms: Collagen alpha-3IV chain, Alpha 3 type IV collagen, Alpha3 type IV collagen, COL4A 3, COL4A3, Collagen IV alpha 3 polypeptide, Collagen type IV alpha 3 Goodpasture antigen, Collagen type IV alpha 3, Goodpasture antigen, OTTHUMP00000195044, Tumstatin, Col4a3, CO4A3_HUMAN.
Background: COL4A3 (Collagen, type IV, alpha 3) belongs to the type IV collagen family. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Type IV collagen is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity.
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基因ID
- 1285
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途径
- Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity
抗原
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