OTUB1 抗体 (Internal Region)
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- 抗原 See all OTUB1 抗体
- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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抗原表位
- AA 20-100, Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OTUB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Otubain-1 is a protein encoded by the OTUB1 gene which is approximately 31,3 kDa. Otubain-1 is localised to the cytoplasm and is involved in deubiquitination, metabolism of proteins, DNA damage and ovarian tumor domain proteases. Otubain-1 is a member of the ovarian tumor superfamily. It interacts with another ubiquitin protease and an E3 ubiquitin ligase whicj inhibits cytokine gene transcription in the immune system. It also plays a key non-catalytic role in DNA repair regulation by inhibiting activity of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of Lys-63-linked histone H2A and H2AX at DNA damage sites. Isoform 1 of otubain-1 is ubiquitously expressed while isoform 2 is expressed only in lymphoid tissues as well as peripheral blood mononuclear cells. Mutations in the OTUB1 gene may result in retinitis pigmentosa. STJ97632 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of otubain-1 protein.
- 特异性
- Otubain-1 Polyclonal Antibody detects endogenous levels of Otubain-1 protein.
- 产品特性
- Rabbit polyclonal to Otubain-1.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human Otubain-1
- 亚型
- IgG
- Top Product
- Discover our top product OTUB1 Primary Antibody
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anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibody
OTUB1 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 5B8 unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibodyOTUB1 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2H1 unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibodyOTUB1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5F7 unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (Internal Region) antibodyOTUB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (AA 1-220) antibodyOTUB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (AA 2-201) antibodyOTUB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibodyOTUB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) antibodyOTUB1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (AA 1-271) antibodyOTUB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C12 unconjugated
anti-OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) (Center) antibodyOTUB1 适用: 人, 小鼠 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:500-1:2000
ELISA 1:10000 - 说明
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Isoform 1 is ubiquitous. Isoform 2 is expressed only in lymphoid tissues such as tonsils, lymph nodes and spleen, as well as peripheral blood mononuclear cells.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
- 别名
- Otubain-1 (OTUB1 产品)
- 别名
- OTB1 antibody, OTU1 antibody, AI850305 antibody, fa19h07 antibody, otub1 antibody, wu:fa19h07 antibody, zgc:92839 antibody, MGC131231 antibody, fb17f04 antibody, otub1l antibody, wu:fb17f04 antibody, zgc:92685 antibody, OTU deubiquitinase, ubiquitin aldehyde binding 1 antibody, OTU domain, ubiquitin aldehyde binding 1 antibody, OTU deubiquitinase, ubiquitin aldehyde binding 1b antibody, OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog antibody, similar to HSPC263 antibody, OTU deubiquitinase, ubiquitin aldehyde binding 1a antibody, OTUB1 antibody, Otub1 antibody, otub1b antibody, otub1.L antibody, otub1 antibody, RGD1565010 antibody, otub1a antibody
- 基因ID
- 55611
- UniProt
- Q96FW1
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