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Caspase 3 抗体 (Internal Region)

CASP3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6281726
发货至: 中国
  • 抗原 See all Caspase 3 (CASP3) 抗体
    Caspase 3 (CASP3)
    抗原表位
    • 19
    • 16
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    AA 171-220, Internal Region
    适用
    • 272
    • 191
    • 147
    • 31
    • 17
    • 10
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    • 9
    • 7
    • 7
    • 5
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    人, 小鼠, 大鼠
    宿主
    • 274
    • 39
    • 4
    • 2
    • 2
    克隆类型
    • 272
    • 48
    多克隆
    标记
    • 152
    • 26
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    • 14
    • 11
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    • 9
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    • 6
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    This Caspase 3 antibody is un-conjugated
    应用范围
    • 246
    • 107
    • 104
    • 85
    • 79
    • 65
    • 48
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    • 26
    • 19
    • 10
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    • 1
    Western Blotting (WB), ELISA
    原理
    Caspase-3 is a protein encoded by the CASP3 gene which is approximately 31,6 kDa. Caspase-3 is localised to the cytoplasm. It is involved in the TNFR1 pathway, apoptosis modulation and signalling and respiratory electron transport. This protein falls under the cysteine-aspartic acid protease family. It is a sequential activatior of caspases and plays a central role in the execution-phase of cell apoptosis. Caspase-3 is highly expressed in lung, spleen, heart, liver and kidney. Mutations in the CASP3 gene may result in bladder urothelial carcinoma and primary effusion lymphoma. STJ96569 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of fragment of Caspase-3 protein.
    特异性
    Caspase-3 Polyclonal Antibody detects endogenous levels of Caspase-3 protein.
    产品特性
    Rabbit polyclonal to Caspase-3.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human Caspase-3.
    亚型
    IgG
    Top Product
    Discover our top product CASP3 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    ELISA 1:20000
    说明

    Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    Caspase 3 (CASP3)
    别名
    Caspase-3 (CASP3 产品)
    别名
    CPP32 antibody, CPP32B antibody, SCA-1 antibody, A830040C14Rik antibody, AC-3 antibody, Apopain antibody, CC3 antibody, Caspase-3 antibody, Lice antibody, Yama antibody, mldy antibody, xcpp32 antibody, casp3 antibody, zgc:100890 antibody, CASP-3 antibody, caspase-3 antibody, caspase 3 antibody, caspase 3 S homeolog antibody, caspase 3, apoptosis-related cysteine peptidase a antibody, caspase 3, apoptosis-related cysteine peptidase antibody, CASP3 antibody, Casp3 antibody, casp3.S antibody, casp3a antibody
    分子量
    17 kDa
    基因ID
    836
    UniProt
    P42574
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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