P27 (AA 140-220) 抗体
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- 抗原
- P27
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抗原表位
- AA 140-220
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA
- 原理
- p27 is a protein encoded by the CDKN1B gene which is approximately 22 kDa. p27 is localised to the nucleus and cytoplasm. It is involved in CDK-mediated phosphorylation and removal of Cdc6, RET signalling, GAB1 signalosome and cell cycle role of SCF complex in cell cycle regulation. It is a cyclin-dependent kinase inhibitor that binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, which are important in controlling the cell cycle progression at G1. p27 is expressed in all tissues with the highest levels in skeletal muscles. Mutations in the CDKN1B gene may result in multiple endocrine neoplasia. STJ94866 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p27 protein.
- 特异性
- P27 Polyclonal Antibody detects endogenous levels of p27 protein.
- 产品特性
- Rabbit polyclonal to p27.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human p27 around the non-phosphorylation site of T198.
- 亚型
- IgG
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anti-P27 antibody
适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p), FACS, IF 宿主: 小鼠 Monoclonal DCS-72-F6-KIP1-769 unconjugated
anti-P27 antibody适用: 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-P27 (Ser235) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P27 (Ser235), (Ser236) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P27 (Ser237) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P27 (pThr198) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P27 (pThr187) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P27 (pSer10) antibody适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P27 antibody适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p), FACS, IF 宿主: 小鼠 Monoclonal DCS-72-F6 unconjugated
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- 应用备注
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WB 1:500-1:2000
ELISA 1:5000 - 说明
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Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- P27
- 别名
- Kip1 antibody, p27 antibody, cyclin dependent kinase inhibitor 1B antibody, CDKN1B antibody
- 物质类
- Viral Protein
- 分子量
- 27 kDa
- 基因ID
- 1027
- UniProt
- P46527
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