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P27 抗体

适用: 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7249468
发货至: 中国
  • 抗原
    P27
    适用
    • 31
    • 16
    • 15
    • 4
    • 1
    • 1
    人, 大鼠
    宿主
    • 24
    • 8
    克隆类型
    • 24
    • 8
    多克隆
    标记
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 17
    • 15
    • 9
    • 5
    • 4
    • 4
    • 4
    Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse P27 KIP1
    亚型
    IgG
  • 应用备注
    IHC 1:100-1:400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.89 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    P27
    别名
    Kip1 antibody, p27 antibody, cyclin dependent kinase inhibitor 1B antibody, CDKN1B antibody
    物质类
    Viral Protein
    背景
    This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
    UniProt
    P46527, P46414
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