CD63 抗体 (Internal Region)
-
- 抗原 See all CD63 抗体
- CD63
-
抗原表位
- AA 121-170, Internal Region
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CD63 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- CD63 is a protein encoded by the CD63 gene which is approximately 25,6 kDa. CD63 is localised to the cell membrane. It is involved in response to elevated platelet cytosolic Ca2+, the innate immune system and adhesion. This protein falls under the tetraspanin family. Most of these members are characterized by the presence of four hydrophobic domains. It is a cell surface glycoprotein that is known to complex with integrins and may function as a blood platelet activation marker. It also mediates signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD63 is expressed in skin, lung, blood, liver and muscle. Mutations in the CD63 gene may result in mast cell disease. STJ96890 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CD63 protein.
- 特异性
- CD63 Polyclonal Antibody detects endogenous levels of CD63 protein.
- 产品特性
- Rabbit polyclonal to CD63.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human CD63.
- 亚型
- IgG
- Top Product
- Discover our top product CD63 Primary Antibody
-
-
- 应用备注
-
WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000 - 说明
-
Detected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
-