Smad2/3 抗体 (Thr8)
-
- 抗原 See all Smad2/3 (SMAD2/3) products
- Smad2/3 (SMAD2/3) (Smad2/3 Transcription Factor (SMAD2/3))
-
抗原表位
- AA 1-80, Thr8
-
适用
- 人, 大鼠, 小鼠, 猴
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Smad2/3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Smad2/3 is a protein encoded by the SMAD2 gene which is approximately 52,3 kDa. Smad2/3 is localised to the cytoplasm and nucleus. It is involved in TGF-beta receptor signalling which activate SMADs, Th17 cell differentiation and human embryonic stem cell pluripotency. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signalling pathways. This protein mediates the signal of the TGF-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation protein. Smad2/3 is expressed at high levels in skeletal muscle, endothelial cells, heart and placenta. Mutations in the SMAD2 gene may result in Ureteral disease. STJ95697 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Smad2/3 protein.
- 特异性
- Smad2/3 Polyclonal Antibody detects endogenous levels of Smad2/3 protein.
- 产品特性
- Rabbit polyclonal to Smad2/3.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human Smad2/3 around the non-phosphorylation site of T8.
- 亚型
- IgG
-
anti-Smad2/3 Transcription Factor (SMAD2/3) (AA 30-80) antibody
SMAD2/3 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Smad2/3 Transcription Factor (SMAD2/3) (pThr8), (Thr8) antibodySMAD2/3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Smad2/3 Transcription Factor (SMAD2/3) (pThr8) antibodySMAD2/3 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Smad2/3 Transcription Factor (SMAD2/3) (Ser104) antibodySMAD2/3 适用: 人, 大鼠, 小鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Smad2/3 Transcription Factor (SMAD2/3) (AA 1-50) antibodySMAD2/3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Smad2/3 Transcription Factor (SMAD2/3) (N-Term) antibodySMAD2/3 适用: 人, 大鼠, 小鸡, Cow, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000 - 说明
-
Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
- 抗原
- Smad2/3 (SMAD2/3) (Smad2/3 Transcription Factor (SMAD2/3))
- 别名
- Smad2/3 (SMAD2/3 产品)
- 分子量
- 48/60 kDa
- 基因ID
- 4087
- UniProt
- Q15796
-
