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Histone 3 抗体 (H3K4me3)

Name: Histone 3 抗体 (H3K4me3)
SKU: ABIN6266172
Availability: OutOfStock

This anti-Histone 3 antibody is a 兔多克隆 antibody detecting Histone 3 in WB, IF, IHC, ELISA, ChIP, IP 和 ICC. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Western blot analysis of extracts of HeLa, using Histone H3K4me3 Antibody. (Histone 3 抗体 (H3K4me3))

ABIN6277194 at 1/100 staining Human gastric tissue by IHC-P. (Histone 3 抗体 (H3K4me3))

IHC

IF/ICC

3 images

(1 reference)

产品编号 ABIN6266172

发货至: 中国

Quick Overview for Histone 3 抗体 (H3K4me3) (ABIN6266172)

Key Features

High quality Histone 3 Primary Antibody for the detection of H3.
Reliable product with high standard validation data

抗原

See all Histone 3 (H3) 抗体

Histone 3 (H3) (Histone H3 (H3))

适用

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人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Histone 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Discover our top product H3 Primary Antibody

抗原表位
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H3K4me3

特异性

Tri-Methyl-Histone H3 (Lys4)/H3K4me3 Antibody detects endogenous levels of Tri-Methyl-Histone H3 only when methylated at Lys4.

预测反应

Horse,Sheep,Rabbit

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthetic methylated peptide derived from human Tri-Methyl-Histone H3 around the methylation site of Lys4.

亚型

IgG

Product Specific Information

What can the Histone 3 Antibody ABIN6266172 be used for?

This polyclonal Histone 3 Antibody detects Histone 3. The Histone 3 Antibody has been validated for various applications and can be used for the detection of Histone 3 and derivatives by Western Blotting, Immunofluorescence, Immunohistochemistry, ELISA, Chromatin Immunoprecipitation, Immunoprecipitation, Immunocytochemistry.

What validation data is available for this Histone 3 Antibody?

The Primary Antibody is referenced in 1 publications and is characterized by a proven, very high reliability. It has currently 3 product images that show its performance in a variety of applications. The product is currently available in 100 μL, 200 μL quantities. Histone 3 Antibody for the detection of Histone 3 and derivatives.

What is the function of Histone 3?

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails\; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008].
anti-Histone H3 (H3) (H3K4me) antibody
H3 适用: 人 WB, IF, ChIP, IP, ChIP-seq, CUT&RUN 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K27ac) antibody
H3 适用: 人, Saccharomyces cerevisiae WB, IF, ChIP, DB, ICC, ChIP-seq, CUT&RUN, CUT&Tag 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (3meLys4) antibody
H3 适用: 人, Saccharomyces cerevisiae WB, IF, ChIP, DB, ICC, ChIP-seq, CUT&RUN 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K9ac) antibody
H3 适用: 人, 小鼠 WB, IF, ChIP, DB, ICC, ChIP-seq, CUT&RUN, CUT&Tag 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K36me3) antibody
H3 适用: 人, 小鼠 WB, ChIP, DB, ChIP-seq, CUT&RUN, CUT&Tag 宿主: 小鼠 Monoclonal MABI 0333 unconjugated

anti-Histone H3 (H3) (AA 71-136) antibody
H3 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K4me3) antibody
H3 适用: 人, 小鼠, Saccharomyces cerevisiae WB, IF, ChIP, DB, ICC, ChIP-seq, CUT&RUN, CUT&Tag 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (C-Term) antibody
H3 适用: 人 WB, IHC, ChIP, IP 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3K9me2) antibody
H3 适用: 人 WB, IF, IHC, ChIP, IP, ChIP-seq 宿主: 兔 Polyclonal unconjugated

anti-Histone H3 (H3) (H3R2me2) antibody
H3 适用: 人 WB, IF, ChIP, IP, ChIP-seq 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:50-1:200, IP 1:50-1:200, CHIP 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Yi, Guo, Guo, Sun, Yang, Wang, Li, Xie, Cai, Wang: "EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion." in: Scientific reports, Vol. 7, Issue 1, pp. 3568, (2017) (PubMed).
抗原

Histone 3 (H3) (Histone H3 (H3))

别名

HIST3H3

背景

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST3H3

分子量

15kDa

基因ID

8290

UniProt

Q16695