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Histone 3 抗体 (H3K27me3)

H3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ChIP, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6266167
发货至: 中国
  • 抗原 See all Histone 3 (H3) 抗体
    Histone 3 (H3)
    抗原表位
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    H3K27me3
    适用
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    人, 小鼠, 大鼠
    宿主
    • 1183
    • 242
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    克隆类型
    • 1108
    • 328
    • 1
    多克隆
    标记
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    This Histone 3 antibody is un-conjugated
    应用范围
    • 1034
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    特异性
    Tri-Methyl-Histone H3 (Lys27)/H3K27me3 Antibody detects endogenous levels of Tri-Methyl-Histone H3 only when methylated at Lys27.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthetic methylated peptide derived from human Tri-Methyl-Histone H3 around the methylation site of Lys27.
    亚型
    IgG
    Top Product
    Discover our top product H3 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:50-1:200, IP 1:50-1:200, CHIP 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • Chen, Liu, Lu, Luo, Wang, Wang, Cai, Yang, Xie, Zhang, Yun: "HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis." in: Molecular oncology, Vol. 11, Issue 9, pp. 1225-1240, (2018) (PubMed).

  • 抗原
    Histone 3 (H3)
    别名
    HIST3H3 (H3 产品)
    别名
    H-3 antibody, histocompatibility 3 antibody, H3 antibody
    背景

    Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Gene: HIST3H3

    分子量
    15kDa
    基因ID
    8290
    UniProt
    Q16695
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