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TRAF1 抗体 (C-Term)

This anti-TRAF1 antibody is a 兔 多克隆 antibody detecting TRAF1 in WB, IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6265702
发货至: 中国

Quick Overview for TRAF1 抗体 (C-Term) (ABIN6265702)

抗原

See all TRAF1 抗体
TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

适用

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人, 小鼠, 大鼠

宿主

  • 48
  • 29
  • 1

克隆类型

  • 51
  • 27
多克隆

标记

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This TRAF1 antibody is un-conjugated

应用范围

  • 33
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 24
    • 15
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    • 1
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    C-Term

    特异性

    TRAF1 Antibody detects endogenous levels of total TRAF1.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TRAF1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

    别名

    TRAF1

    背景

    Description: Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

    Gene: TRAF1

    分子量

    46 kDa

    基因ID

    7185

    UniProt

    Q13077

    途径

    NF-kappaB Signaling, Apoptosis, Cell-Cell Junction Organization, Asymmetric Protein Localization
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