TAP2 抗体 (Internal Region)
-
- 抗原 See all TAP2 抗体
- TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))
-
抗原表位
- Internal Region
- 适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TAP2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- TAP2 Antibody detects endogenous levels of total TAP2.
- 预测反应
- Pig,Horse,Rabbit,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human TAP2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product TAP2 Primary Antibody
-
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 430-680) antibody
TAP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 451-550) antibodyTAP2 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 100-134) antibodyTAP2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56970 unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 467-703) antibodyTAP2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) antibodyTAP2 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 473-615) antibodyTAP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) antibodyTAP2 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 1-686) antibodyTAP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 468-686) antibodyTAP2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) antibodyTAP2 适用: 人, 大鼠, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))
- 别名
- TAP2 (TAP2 产品)
- 别名
- ABC18 antibody, ABCB3 antibody, APT2 antibody, D6S217E antibody, PSF-2 antibody, PSF2 antibody, RING11 antibody, AI462429 antibody, Abcb3 antibody, Ham-2 antibody, Ham2 antibody, MTP2 antibody, Tap-2 antibody, Y1 antibody, jas antibody, Cim antibody, transporter 2, ATP binding cassette subfamily B member antibody, transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) antibody, TAP2 antibody, Tap2 antibody
- 背景
-
Description: Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. Inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association.
Gene: TAP2
- 分子量
- 76kDa
- 基因ID
- 6891
- UniProt
- Q03519
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-
