SH2D1A 抗体 (Internal Region)
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- 抗原 See all SH2D1A 抗体
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SH2D1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- SH2D1A Antibody detects endogenous levels of total SH2D1A.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SH2D1A, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SH2D1A Primary Antibody
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anti-SH2 Domain Containing 1A (SH2D1A) (AA 1-128) antibody
SH2D1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 1-128) antibodySH2D1A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 11-124) antibodySH2D1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) antibodySH2D1A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (C-Term) antibodySH2D1A 适用: 人, 猴, 兔, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 18-115) antibodySH2D1A 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 1-128) antibodySH2D1A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (Internal Region) antibodyVerified SH2D1A 适用: 人 WB, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) antibodySH2D1A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SH2 Domain Containing 1A (SH2D1A) (AA 85-114), (C-Term) antibodySH2D1A 适用: 人 WB 宿主: 兔 Polyclonal RB41923 unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
- 别名
- SH2D1A (SH2D1A 产品)
- 别名
- DSHP antibody, EBVS antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, SAP/SH2D1A antibody, XLP antibody, XLPD antibody, RGD1562408 antibody, Gm686 antibody, SH2D1A antibody, SH2 domain containing 1A antibody, SH2D1A antibody, Sh2d1a antibody
- 背景
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Description: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2 (PubMed:11806999). However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1 (PubMed:12458214). Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions. Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation. In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells (By similarity). May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.
Gene: SH2D1A
- 分子量
- 14kDa
- 基因ID
- 4068
- UniProt
- O60880
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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