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ROS1 抗体 (C-Term)

The 兔 多克隆 anti-ROS1 antibody is suitable to detect ROS1 in samples from 人 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN6264807
发货至: 中国
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Quick Overview for ROS1 抗体 (C-Term) (ABIN6264807)

抗原

See all ROS1 抗体
ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

适用

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人, 大鼠

宿主

  • 49
  • 12
  • 1

克隆类型

  • 49
  • 13
多克隆

标记

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This ROS1 antibody is un-conjugated

应用范围

  • 38
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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    特异性

    ROS Antibody detects endogenous levels of total ROS.

    预测反应

    Pig,Horse,Sheep

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ROS, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

    别名

    ROS1

    背景

    Description: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.

    Gene: ROS1

    分子量

    263kDa

    基因ID

    6098

    UniProt

    P08922

    途径

    RTK signaling
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