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ROS1 抗体 (AA 2231-2347)

The 兔 多克隆 anti-ROS1 antibody (ABIN741225) specifically detects ROS1 in WB, ELISA, IHC (p) 和 FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN741225
发货至: 中国
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Quick Overview for ROS1 抗体 (AA 2231-2347) (ABIN741225)

抗原

See all ROS1 抗体
ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

适用

  • 47
  • 31
  • 25
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 49
  • 12
  • 1

克隆类型

  • 49
  • 13
多克隆

标记

  • 30
  • 6
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ROS1 antibody is un-conjugated

应用范围

  • 38
  • 17
  • 14
  • 9
  • 9
  • 7
  • 7
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 8
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2231-2347

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human c-Ros

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

    别名

    c-Ros

    背景

    Synonyms: ROS, MCF3, c-ros-1, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, Receptor tyrosine kinase c-ros oncogene 1, c-Ros receptor tyrosine kinase, ROS1

    Background: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.

    基因ID

    6098

    UniProt

    P08922

    途径

    RTK signaling
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