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ROS1 抗体 (AA 79-248)

This 兔 多克隆 antibody specifically detects ROS1 in ELISA 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7166495
发货至: 中国
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Quick Overview for ROS1 抗体 (AA 79-248) (ABIN7166495)

抗原

See all ROS1 抗体
ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ROS1 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 79-248

    原理

    ROS1 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Proto-oncogene tyrosine-protein kinase ROS protein (79-248AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

    别名

    ROS1

    背景

    Background: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.

    Aliases: c ros 1 antibody, c ros antibody, c ros oncogene 1 receptor tyrosine kinase antibody, c Ros receptor tyrosine kinase antibody, c ros1 antibody, MCF 3 antibody, MCF3 antibody, Oncogene ROS antibody, OTTHUMP00000017814 antibody, OTTHUMP00000017815 antibody, OTTHUMP00000040389 antibody, Proto oncogene c ros 1 protein antibody, Proto oncogene c Ros antibody, Proto oncogene tyrosine protein kinase ROS antibody, Proto oncogene tyrosine protein kinase ROS precursor antibody, Proto-oncogene c-Ros-1 antibody, Proto-oncogene tyrosine-protein kinase ROS antibody, Receptor tyrosine kinase c ros oncogene 1 antibody, Ros 1 antibody, ROS 1C antibody, ROS antibody, ROS proto oncogene 1 , receptor tyrosine kinase antibody, ROS_HUMAN antibody, ROS1 antibody, ROS1C antibody, Transmembrane tyrosine specific protein kinase antibody, v ros avian UR2 sarcoma virus oncogene homolog 1 antibody, v ros UR2 sarcoma virus oncogene homolog 1 antibody

    UniProt

    P08922

    途径

    RTK signaling
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