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ROS1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects ROS1 in WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN3030232
发货至: 中国
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Quick Overview for ROS1 抗体 (C-Term) (ABIN3030232)

抗原

See all ROS1 抗体
ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

适用

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宿主

  • 50
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克隆类型

  • 50
  • 13
多克隆

标记

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This ROS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    纯化方法

    Antigen affinity purified

    免疫原

    This ROS1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1744-1777 amino acids from the C-terminal region of human ROS1.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the ROS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the ROS1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))

    别名

    ROS1

    背景

    Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.

    UniProt

    P08922

    途径

    RTK signaling
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