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Mahogunin RING Finger Protein 1 抗体 (Internal Region)

MGRN1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264784
发货至: 中国
  • 抗原 See all Mahogunin RING Finger Protein 1 (MGRN1) 抗体
    Mahogunin RING Finger Protein 1 (MGRN1) (Mahogunin, Ring Finger 1 (MGRN1))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 15
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 11
    • 4
    克隆类型
    • 12
    • 3
    多克隆
    标记
    • 15
    This Mahogunin RING Finger Protein 1 antibody is un-conjugated
    应用范围
    • 14
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    RNF156 Antibody detects endogenous levels of total RNF156.
    预测反应
    Pig,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RNF156, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MGRN1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Mahogunin RING Finger Protein 1 (MGRN1) (Mahogunin, Ring Finger 1 (MGRN1))
    别名
    MGRN1 (MGRN1 产品)
    别名
    RNF156 antibody, 2610042J20Rik antibody, mKIAA0544 antibody, md antibody, nc antibody, RGD1311862 antibody, mgrn1 antibody, wu:fi38c03 antibody, zgc:55978 antibody, mahogunin ring finger 1 antibody, mahogunin, ring finger 1 antibody, mahogunin ring finger 1, E3 ubiquitin protein ligase S homeolog antibody, mahogunin ring finger 1, E3 ubiquitin protein ligase antibody, mahogunin, ring finger 1a antibody, MGRN1 antibody, Mgrn1 antibody, mgrn1.S antibody, mgrn1 antibody, mgrn1a antibody
    背景

    Description: E3 ubiquitin-protein ligase. Mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. Plays a role in the regulation of endosome-to-lysosome trafficking. Impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production. Does not inhibit ADRB2-signaling. Does not promote MC1R ubiquitination. Acts also as a negative regulator of hedgehog signaling (By similarity).

    Gene: MGRN1

    分子量
    66-72 kDa,55 kDa
    基因ID
    23295
    UniProt
    O60291
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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