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Mahogunin RING Finger Protein 1 抗体 (AA 400-450)

MGRN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7451872
发货至: 中国
  • 抗原 See all Mahogunin RING Finger Protein 1 (MGRN1) 抗体
    Mahogunin RING Finger Protein 1 (MGRN1) (Mahogunin, Ring Finger 1 (MGRN1))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-450
    适用
    • 14
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 10
    • 4
    克隆类型
    • 11
    • 3
    多克隆
    标记
    • 14
    This Mahogunin RING Finger Protein 1 antibody is un-conjugated
    应用范围
    • 13
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-MGRN1 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 400 and 450
    亚型
    IgG
    Top Product
    Discover our top product MGRN1 Primary Antibody
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    Mahogunin RING Finger Protein 1 (MGRN1) (Mahogunin, Ring Finger 1 (MGRN1))
    别名
    MGRN1 (MGRN1 产品)
    别名
    RNF156 antibody, 2610042J20Rik antibody, mKIAA0544 antibody, md antibody, nc antibody, RGD1311862 antibody, mgrn1 antibody, wu:fi38c03 antibody, zgc:55978 antibody, mahogunin ring finger 1 antibody, mahogunin, ring finger 1 antibody, mahogunin ring finger 1, E3 ubiquitin protein ligase S homeolog antibody, mahogunin ring finger 1, E3 ubiquitin protein ligase antibody, mahogunin, ring finger 1a antibody, MGRN1 antibody, Mgrn1 antibody, mgrn1.S antibody, mgrn1 antibody, mgrn1a antibody
    背景
    Background: MGRN1 (mahogunin RING finger protein 1) is an E3 ubiquitin-protein ligase that mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. MGRN1 plays a role in the regulation of endosome-to-lysosome trafficking. It impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production but does not promote MC1R ubiquitination [taken from the Universal Protein Resource (UniProt) O60291].
    基因ID
    23295
    NCBI登录号
    NP_001135761
    UniProt
    O60291
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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