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RAB8A 抗体

RAB8A 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264591
发货至: 中国
  • 抗原 See all RAB8A 抗体
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    适用
    • 37
    • 11
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    • 5
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    • 4
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    • 3
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 21
    • 11
    • 4
    克隆类型
    • 26
    • 11
    多克隆
    标记
    • 23
    • 2
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    • 2
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    • 2
    • 2
    This RAB8A antibody is un-conjugated
    应用范围
    • 21
    • 11
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    RAB8A Antibody detects endogenous levels of total RAB8A
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RAB8A
    亚型
    IgG
    Top Product
    Discover our top product RAB8A Primary Antibody
  • 应用备注
    WB 1:1000-3000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    别名
    RAB8A (RAB8A 产品)
    别名
    rab8A antibody, DDBDRAFT_0206521 antibody, DDBDRAFT_0214885 antibody, DDB_0206521 antibody, DDB_0214885 antibody, HSH2D antibody, mel antibody, rab8 antibody, c-mel antibody, MEL antibody, RAB8 antibody, zgc:162699 antibody, AA409338 antibody, Mel antibody, Rab8 antibody, rab8A protein antibody, Rab GTPase antibody, RAB8A, member RAS oncogene family antibody, RAB8A, member RAS oncogene family S homeolog antibody, rab8A antibody, RAB8A antibody, rab8a antibody, rab8a.S antibody, Rab8a antibody
    背景

    Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (PubMed:20890297). Together with MYO5B and RAB11A participates in epithelial cell polarization (PubMed:21282656). Plays an important role in ciliogenesis (PubMed:21844891). Together with MICALL2, may also regulate adherens junction assembly (By similarity). May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose homeostasis (By similarity). Involved in autophagy (PubMed:27103069).

    Gene: RAB8A

    分子量
    24 kDa
    基因ID
    4218
    UniProt
    P61006
    途径
    M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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