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PVRL2 抗体 (Internal Region)

PVRL2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264532
发货至: 中国
  • 抗原 See all PVRL2 抗体
    PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
    抗原表位
    • 16
    • 7
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    • 2
    • 2
    • 1
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    Internal Region
    适用
    • 71
    • 25
    • 13
    • 4
    • 2
    • 1
    宿主
    • 52
    • 14
    • 11
    克隆类型
    • 43
    • 33
    • 1
    多克隆
    标记
    • 37
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    This PVRL2 antibody is un-conjugated
    应用范围
    • 52
    • 38
    • 17
    • 16
    • 15
    • 15
    • 14
    • 11
    • 7
    • 6
    • 2
    • 2
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    PVRL2 Antibody detects endogenous levels of total PVRL2.
    预测反应
    Pig,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PVRL2, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PVRL2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
    别名
    NECTIN2 (PVRL2 产品)
    别名
    prr2 antibody, AI325026 antibody, AI987993 antibody, Cd112 antibody, MPH antibody, Pvr antibody, Pvs antibody, nectin-2 antibody, CD112 antibody, HVEB antibody, PRR2 antibody, PVRR2 antibody, nectin cell adhesion molecule 2 antibody, Nectin2 antibody, NECTIN2 antibody
    背景

    Description: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705). Probable cell adhesion protein (PubMed:9657005).

    Gene: NECTIN2

    分子量
    57kDa
    基因ID
    5819
    UniProt
    Q92692
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
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