PVRL2 抗体 (AA 58-212)
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北京 101111
Quick Overview for PVRL2 抗体 (AA 58-212) (ABIN5611344)
抗原
See all PVRL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 58-212
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原理
- CD112 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD112 (AA: 58-212) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
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别名
- CD112
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背景
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This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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分子量
- 57.7 kDa
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基因ID
- 5819
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UniProt
- Q92692
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
抗原
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